PrP-Res – Page 2 – Application of a small molecule inhibitor screen approach

Apart from stem cells giving rise to differentiated cells, it has also been observed that more differentiated cells can de-differentiate into stem cells, both in healthy cells and tumors, elements of which have also been investigated mathematically

Posted on June 5, 2021 by Courtney Roberts

Apart from stem cells giving rise to differentiated cells, it has also been observed that more differentiated cells can de-differentiate into stem cells, both in healthy cells and tumors, elements of which have also been investigated mathematically. presence of de-differentiation, the fixation probability of a neutral mutant is lower than Continue Reading

Supplementary Components1

Posted on April 20, 2021 by Courtney Roberts

Supplementary Components1. factors RIF1 and PTIP. Depletion of FOXK1 impairs DNA restoration and induces jeopardized cell survival upon DNA damage. Overexpression of FOXK1 diminishes 53BP1 foci formation, that leads to level of resistance to PARPis and elevation of HR in BRCA1-lacking cells and reduced telomere fusion in TRF2-depleted cells. Collectively, Continue Reading