Supplementary Components1

Supplementary Components1. factors RIF1 and PTIP. Depletion of FOXK1 impairs DNA restoration and induces jeopardized cell survival upon DNA damage. Overexpression of FOXK1 diminishes 53BP1 foci formation, that leads to level of resistance to PARPis and elevation of HR in BRCA1-lacking cells and reduced telomere fusion in TRF2-depleted cells. Collectively, Continue Reading