The kinase activity assay unveiled that C817 could inhibit Abl kinase activity, either wild site or type mutations in Q252H, Con253F, and T315I

Posted on by Courtney Roberts

The kinase activity assay unveiled that C817 could inhibit Abl kinase activity, either wild site or type mutations in Q252H, Con253F, and T315I. progenitor/stem cells. Outcomes: C817 potently inhibited both WT and mutant (Q252H, Y253F, and T315I) Abl kinase actions within a non-ATP competitive way using the beliefs of IC50 Continue Reading