Arthrogryposis at birth and other congenital malformations occur in nearly one-third [66,69,75] but are not associated with specific mutations. agrin, MuSK, Dok-7, GFPT1, plectin, fetal akinesia syndrome == 1. Introduction == In each congenital myasthenic syndrome (CMS) the security margin of neuromuscular transmission is compromised by one or more mechanisms. Continue Reading