Additionally, plaque assays confirmed the production of infectious progeny virus and showed that VPA increased HSVGM-CSF replication (Figure?3C), with potentiation by VPA getting most apparent in A375 cells, that have been less permissive to viral replication inherently. from the histone deacetylase inhibitor valproic acidity (VPA) to HSVGM-CSF treatment of tumor Continue Reading