5-aminolevulinic acid solution (5-ALA) has recently been employed for photodynamic diagnosis (ALA-PDD) and photodynamic therapy (ALA-PDT) of various forms of cancer because hyperproliferating tumor cells do not utilize oxidative phosphorylation and don’t efficiently produce heme; instead, they accumulate protoporphyrin IX (PpIX), which is a precursor of heme that is triggered by violet light irradiation that results in the production of reddish fluorescence and singlet oxygen

Posted on by Courtney Roberts

5-aminolevulinic acid solution (5-ALA) has recently been employed for photodynamic diagnosis (ALA-PDD) and photodynamic therapy (ALA-PDT) of various forms of cancer because hyperproliferating tumor cells do not utilize oxidative phosphorylation and don’t efficiently produce heme; instead, they accumulate protoporphyrin IX (PpIX), which is a precursor of heme that is triggered Continue Reading

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